Hydrochlorothiazide vs Ondansetron

## Hydrochlorothiazide vs Ondansetron: Overview

This comparison examines the pharmacological differences between **Hydrochlorothiazide** and **Ondansetron**.

## Mechanism of Action

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

**Ondansetron**: Selective 5-HT3 receptor antagonist.

## Pharmacokinetics

**Half-life**: Hydrochlorothiazide — 6-15 hours; Ondansetron — 3-5 hours.

## Chemical Properties

**Molecular Formula**: Hydrochlorothiazide — C7H8ClN3O4S2; Ondansetron — C18H19N3O.

**Molecular Weight**: Hydrochlorothiazide — 297.7400 g/mol; Ondansetron — 293.3660 g/mol.

**Type**: Hydrochlorothiazide — Small molecule; Ondansetron — Small molecule.