Hydrochlorothiazide vs Pravastatin

Hydrochlorothiazide vs Pravastatin: Overview

This comparison examines the pharmacological differences between Hydrochlorothiazide and Pravastatin.

Mechanism of Action

Hydrochlorothiazide: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

Pravastatin: Competitive inhibitor of HMG-CoA reductase.

Pharmacokinetics

Half-life: Hydrochlorothiazide — 6-15 hours; Pravastatin — 1.8 hours.

Chemical Properties

Molecular Formula: Hydrochlorothiazide — C7H8ClN3O4S2; Pravastatin — C23H36O7.

Molecular Weight: Hydrochlorothiazide — 297.7400 g/mol; Pravastatin — 424.5280 g/mol.

Type: Hydrochlorothiazide — Small molecule; Pravastatin — Small molecule.