Hydrochlorothiazide vs Prednisone

Hydrochlorothiazide vs Prednisone: Overview

This comparison examines the pharmacological differences between Hydrochlorothiazide and Prednisone.

Mechanism of Action

Hydrochlorothiazide: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

Prednisone: Synthetic corticosteroid; suppresses inflammation via glucocorticoid receptor.

Pharmacokinetics

Half-life: Hydrochlorothiazide — 6-15 hours; Prednisone — 2-3 hours.

Chemical Properties

Molecular Formula: Hydrochlorothiazide — C7H8ClN3O4S2; Prednisone — C21H26O5.

Molecular Weight: Hydrochlorothiazide — 297.7400 g/mol; Prednisone — 358.4280 g/mol.

Type: Hydrochlorothiazide — Small molecule; Prednisone — Small molecule.