Hydrochlorothiazide vs Sumatriptan

## Hydrochlorothiazide vs Sumatriptan: Overview

This comparison examines the pharmacological differences between **Hydrochlorothiazide** and **Sumatriptan**.

## Mechanism of Action

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

**Sumatriptan**: Selective 5-HT1B/1D receptor agonist.

## Pharmacokinetics

**Half-life**: Hydrochlorothiazide — 6-15 hours; Sumatriptan — 2.5 hours.

## Chemical Properties

**Molecular Formula**: Hydrochlorothiazide — C7H8ClN3O4S2; Sumatriptan — C14H21N3O2S.

**Molecular Weight**: Hydrochlorothiazide — 297.7400 g/mol; Sumatriptan — 295.4020 g/mol.

**Type**: Hydrochlorothiazide — Small molecule; Sumatriptan — Small molecule.