Hydrochlorothiazide vs Vancomycin

## Hydrochlorothiazide vs Vancomycin: Overview

This comparison examines the pharmacological differences between **Hydrochlorothiazide** and **Vancomycin**.

## Mechanism of Action

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

**Vancomycin**: Glycopeptide antibiotic inhibiting cell wall synthesis by binding D-Ala-D-Ala terminus of peptidoglycan precursors.

## Pharmacokinetics

**Half-life**: Hydrochlorothiazide — 6-15 hours; Vancomycin — 4-6 hours.

## Chemical Properties

**Molecular Formula**: Hydrochlorothiazide — C7H8ClN3O4S2; Vancomycin — C66H75Cl2N9O24.

**Molecular Weight**: Hydrochlorothiazide — 297.7400 g/mol; Vancomycin — 1449.2500 g/mol.

**Type**: Hydrochlorothiazide — Small molecule; Vancomycin — Small molecule.