Hydromorphone vs Oxycodone

## Hydromorphone vs Oxycodone: Overview

This comparison examines the pharmacological differences between **Hydromorphone** and **Oxycodone**.

## Mechanism of Action

**Hydromorphone**: Semisynthetic mu-opioid receptor agonist approximately 5 times more potent than morphine.

**Oxycodone**: Semisynthetic mu-opioid receptor agonist.

## Pharmacokinetics

**Half-life**: Hydromorphone — 2-3 hours; Oxycodone — 3-5 hours.

## Chemical Properties

**Molecular Formula**: Hydromorphone — C17H19NO3; Oxycodone — C18H21NO4.

**Molecular Weight**: Hydromorphone — 285.3380 g/mol; Oxycodone — 315.3640 g/mol.

**Type**: Hydromorphone — Small molecule; Oxycodone — Small molecule.