Ibuprofen vs Tramadol

## Ibuprofen vs Tramadol: Overview

This comparison examines the pharmacological differences between **Ibuprofen** and **Tramadol**.

## Mechanism of Action

**Ibuprofen**: Non-selective COX inhibitor reducing prostaglandin synthesis.

**Tramadol**: Mu-opioid receptor agonist and serotonin-norepinephrine reuptake inhibitor.

## Pharmacokinetics

**Half-life**: Ibuprofen — 2-4 hours; Tramadol — 5-7 hours.

## Chemical Properties

**Molecular Formula**: Ibuprofen — C13H18O2; Tramadol — C16H25NO2.

**Molecular Weight**: Ibuprofen — 206.2810 g/mol; Tramadol — 263.3750 g/mol.

**Type**: Ibuprofen — Small molecule; Tramadol — Small molecule.