Lisinopril vs Sildenafil

## Lisinopril vs Sildenafil: Overview

This comparison examines the pharmacological differences between **Lisinopril** and **Sildenafil**.

## Mechanism of Action

**Lisinopril**: ACE inhibitor preventing conversion of angiotensin I to angiotensin II.

**Sildenafil**: Selective PDE5 inhibitor increasing cGMP.

## Pharmacokinetics

**Half-life**: Lisinopril — 12 hours; Sildenafil — 4 hours.

## Chemical Properties

**Molecular Formula**: Lisinopril — C21H31N3O5; Sildenafil — C22H30N6O4S.

**Molecular Weight**: Lisinopril — 405.4900 g/mol; Sildenafil — 474.5800 g/mol.

**Type**: Lisinopril — Small molecule; Sildenafil — Small molecule.