Losartan vs Tofacitinib

## Losartan vs Tofacitinib: Overview

This comparison examines the pharmacological differences between **Losartan** and **Tofacitinib**.

## Mechanism of Action

**Losartan**: Angiotensin II receptor type 1 antagonist.

**Tofacitinib**: Pan-JAK inhibitor with preference for JAK1 and JAK3 blocking pro-inflammatory cytokine signaling.

## Pharmacokinetics

**Half-life**: Losartan — 2 hours; Tofacitinib — 3.2 hours.

## Chemical Properties

**Molecular Formula**: Losartan — C22H23ClN6O; Tofacitinib — C16H20N6O.

**Molecular Weight**: Losartan — 422.9200 g/mol; Tofacitinib — 312.3700 g/mol.

**Type**: Losartan — Small molecule; Tofacitinib — Small molecule.