Metformin vs Rofecoxib

## Metformin vs Rofecoxib: Overview

This comparison examines the pharmacological differences between **Metformin** and **Rofecoxib**.

## Mechanism of Action

**Metformin**: Activates AMP-activated protein kinase, decreasing hepatic glucose production.

## Pharmacokinetics

**Half-life**: Metformin — 4-9 hours; Rofecoxib — N/A.

## Chemical Properties

**Molecular Formula**: Metformin — C4H11N5; Rofecoxib — N/A.

**Molecular Weight**: Metformin — 129.1640 g/mol; Rofecoxib — N/A.

**Type**: Metformin — Small molecule; Rofecoxib — Small molecule.