Norfloxacin vs Tacrolimus

## Norfloxacin vs Tacrolimus: Overview

This comparison examines the pharmacological differences between **Norfloxacin** and **Tacrolimus**.

## Mechanism of Action

**Norfloxacin**: Second-generation fluoroquinolone inhibiting bacterial DNA gyrase and topoisomerase IV.

**Tacrolimus**: Calcineurin inhibitor binding FKBP12; suppresses IL-2 transcription.

## Pharmacokinetics

**Half-life**: Norfloxacin — 3-4 hours; Tacrolimus — 12 hours.

## Chemical Properties

**Molecular Formula**: Norfloxacin — C16H18FN3O3; Tacrolimus — C44H69NO12.

**Molecular Weight**: Norfloxacin — 319.3310 g/mol; Tacrolimus — 804.0180 g/mol.

**Type**: Norfloxacin — Small molecule; Tacrolimus — Small molecule.