Paroxetine vs Sildenafil

## Paroxetine vs Sildenafil: Overview

This comparison examines the pharmacological differences between **Paroxetine** and **Sildenafil**.

## Mechanism of Action

**Paroxetine**: Potent selective serotonin reuptake inhibitor with additional muscarinic and NE reuptake inhibition.

**Sildenafil**: Selective PDE5 inhibitor increasing cGMP.

## Pharmacokinetics

**Half-life**: Paroxetine — 21 hours; Sildenafil — 4 hours.

## Chemical Properties

**Molecular Formula**: Paroxetine — C19H20FNO3; Sildenafil — C22H30N6O4S.

**Molecular Weight**: Paroxetine — 329.3730 g/mol; Sildenafil — 474.5800 g/mol.

**Type**: Paroxetine — Small molecule; Sildenafil — Small molecule.