Sitagliptin vs Sumatriptan

## Sitagliptin vs Sumatriptan: Overview

This comparison examines the pharmacological differences between **Sitagliptin** and **Sumatriptan**.

## Mechanism of Action

**Sitagliptin**: DPP-4 inhibitor increasing incretin levels.

**Sumatriptan**: Selective 5-HT1B/1D receptor agonist.

## Pharmacokinetics

**Half-life**: Sitagliptin — 12.4 hours; Sumatriptan — 2.5 hours.

## Chemical Properties

**Molecular Formula**: Sitagliptin — C16H15F6N5O; Sumatriptan — C14H21N3O2S.

**Molecular Weight**: Sitagliptin — 407.3140 g/mol; Sumatriptan — 295.4020 g/mol.

**Type**: Sitagliptin — Small molecule; Sumatriptan — Small molecule.