Spironolactone vs Telmisartan

## Spironolactone vs Telmisartan: Overview

This comparison examines the pharmacological differences between **Spironolactone** and **Telmisartan**.

## Mechanism of Action

**Spironolactone**: Mineralocorticoid receptor antagonist.

**Telmisartan**: Selective angiotensin II type 1 receptor antagonist; also a partial PPAR-gamma agonist.

## Pharmacokinetics

**Half-life**: Spironolactone — 1.4 hours; Telmisartan — 24 hours.

## Chemical Properties

**Molecular Formula**: Spironolactone — C24H32O4S; Telmisartan — C33H30N4O2.

**Molecular Weight**: Spironolactone — 416.5740 g/mol; Telmisartan — 514.6230 g/mol.

**Type**: Spironolactone — Small molecule; Telmisartan — Small molecule.