Tacrolimus vs Vancomycin

## Tacrolimus vs Vancomycin: Overview

This comparison examines the pharmacological differences between **Tacrolimus** and **Vancomycin**.

## Mechanism of Action

**Tacrolimus**: Calcineurin inhibitor binding FKBP12; suppresses IL-2 transcription.

**Vancomycin**: Glycopeptide antibiotic inhibiting cell wall synthesis by binding D-Ala-D-Ala terminus of peptidoglycan precursors.

## Pharmacokinetics

**Half-life**: Tacrolimus — 12 hours; Vancomycin — 4-6 hours.

## Chemical Properties

**Molecular Formula**: Tacrolimus — C44H69NO12; Vancomycin — C66H75Cl2N9O24.

**Molecular Weight**: Tacrolimus — 804.0180 g/mol; Vancomycin — 1449.2500 g/mol.

**Type**: Tacrolimus — Small molecule; Vancomycin — Small molecule.