Tofacitinib vs Trastuzumab

## Tofacitinib vs Trastuzumab: Overview

This comparison examines the pharmacological differences between **Tofacitinib** and **Trastuzumab**.

## Mechanism of Action

**Tofacitinib**: Pan-JAK inhibitor with preference for JAK1 and JAK3 blocking pro-inflammatory cytokine signaling.

**Trastuzumab**: Anti-HER2 monoclonal antibody inhibiting receptor signaling.

## Pharmacokinetics

**Half-life**: Tofacitinib — 3.2 hours; Trastuzumab — 28 days.

## Chemical Properties

**Molecular Formula**: Tofacitinib — C16H20N6O; Trastuzumab — N/A.

**Molecular Weight**: Tofacitinib — 312.3700 g/mol; Trastuzumab — N/A.

**Type**: Tofacitinib — Small molecule; Trastuzumab — Antibody.