Ambenonium Chloride
The chloride salt form of ambenonium, a cholinesterase inhibitor used in the management of myasthenia gravis to increase acetylcholine availability at neuromuscular junctions. This formulation provides the same symptomatic relief of muscle weakness as the parent compound and has a longer duration of action than some other anticholinesterase agents.
Molekularmasse
608,5000 g/mol
TPSA
58,20 Ų
Wirkmechanismus
Blocks neuromuscular transmission at the motor end plate by competing with acetylcholine for nicotinic receptor binding sites, producing skeletal muscle relaxation and paralysis.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Blocks neuromuscular transmission at the motor end plate by competing with acetylcholine for nicotinic receptor binding sites, producing skeletal muscle relaxation and paralysis.
2D-Struktur
Cite this structure
Embed this structure
SMILES
CC[N+](CC)(CCNC(=O)C(=O)NCC[N+](CC)(CC)Cc1ccccc1Cl)Cc1ccccc1Cl.[Cl-].[Cl-]
InChI
InChI=1S/C28H40Cl2N4O2.2ClH/c1-5-33(6-2,21-23-13-9-11-15-25(23)29)19-17-31-27(35)28(36)32-18-20-34(7-3,8-4)22-24-14-10-12-16-26(24)30;;/h9-16H,5-8,17-22H2,1-4H3;2*1H
Molecular Formula
C28H42Cl4N4O2
HBD / HBA
2 / 4
Rotierbare Bindungen
14
Schwere Atome
38
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Häufig gestellte Fragen
The chloride salt form of ambenonium, a cholinesterase inhibitor used in the management of myasthenia gravis to increase acetylcholine availability at neuromuscular junctions. This formulation provides the same symptomatic relief of muscle weakness as the parent compound and has a longer duration of action than some other anticholinesterase agents.
Blocks neuromuscular transmission at the motor end plate by competing with acetylcholine for nicotinic receptor binding sites, producing skeletal muscle relaxation and paralysis.
Yes, Ambenonium Chloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200541. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 8288. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
Medizinischer Haftungsausschluss
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
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