Apraclonidine Hydrochloride

CHEMBL1200379 Phase 4 Zugelassen Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

281.6 g/mol

LogP

—

Phase

4

The hydrochloride salt of apraclonidine, an ophthalmic agent that lowers eye pressure by activating alpha-2 receptors to decrease fluid production inside the eye. It is used in the short-term management of glaucoma and after certain eye procedures.

Molekularmasse

281,6000 g/mol

TPSA

62,40 Å²

Therapeutische Bereiche

Glaucoma Hypertension

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

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SMILES

Cl.Nc1cc(Cl)c(N=C2NCCN2)c(Cl)c1

InChI

InChI=1S/C9H10Cl2N4.ClH/c10-6-3-5(12)4-7(11)8(6)15-9-13-1-2-14-9;/h3-4H,1-2,12H2,(H2,13,14,15);1H

Molecular Formula

C9H11Cl3N4

HBD / HBA

4 / 2

Rotierbare Bindungen

2

Schwere Atome

16

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

The hydrochloride salt of apraclonidine, an ophthalmic agent that lowers eye pressure by activating alpha-2 receptors to decrease fluid production inside the eye. It is used in the short-term management of glaucoma and after certain eye procedures.

Yes, Apraclonidine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200379. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 51763. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Struktur

Schnelldaten

Formel: C9H11Cl3N4
Synonyme: 3

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Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.