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Armodafinil

CHEMBL1201192 Phase 4 Zugelassen Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
273.4 g/mol
LogP
1.7
Phase
4

The R-enantiomer of modafinil, a wakefulness-promoting agent that is thought to work by increasing dopamine availability in the brain, helping patients stay awake. It is prescribed for excessive sleepiness associated with narcolepsy, shift work disorder, and sleep apnea.

Molekularmasse

273,4000 g/mol

LogP

1,70

TPSA

79,40 Ų

Lipinski-Regel der Fünf

Bestanden

Therapeutische Bereiche

Non-Small Cell Lung Cancer Parkinson's Disease Schizophrenia Insomnia Multiple Sclerosis Stroke Obesity Lymphoma Major Depressive Disorder Breast Cancer HIV/AIDS Hepatitis C Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
NC(=O)C[S@@+]([O-])C(c1ccccc1)c1ccccc1

                

                

                
                

                    
InChI

                    
InChI=1S/C15H15NO2S/c16-14(17)11-19(18)15(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10,15H,11H2,(H2,16,17)/t19-/m1/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C15H15NO2S

                    

                    
                    

                        
HBD / HBA

                        
1 / 3

                    

                    
                    

                        
Rotierbare Bindungen

                        
5

                    

                    
                    
                    

                        
Schwere Atome

                        
19

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Häufig gestellte Fragen

                

                    
                    

                        
                        

                            
The R-enantiomer of modafinil, a wakefulness-promoting agent that is thought to work by increasing dopamine availability in the brain, helping patients stay awake. It is prescribed for excessive sleepiness associated with narcolepsy, shift work disorder, and sleep apnea.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Armodafinil is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1201192.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 9690109.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Medizinischer Haftungsausschluss

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.