Chloroprocaine
A short-acting local anesthetic of the ester class that blocks sodium channels to reversibly inhibit nerve conduction, used primarily for epidural and spinal anesthesia in obstetric procedures. Its rapid hydrolysis by plasma cholinesterases results in a short duration of action and low systemic toxicity. It is particularly valued in obstetrics due to its rapid onset and safety profile for the neonate.
Molekularmasse
270,7500 g/mol
LogP
2,90
TPSA
55,60 Ų
Lipinski-Regel der Fünf
Bestanden
Therapeutische Bereiche
Wirkmechanismus
Blocks voltage-gated sodium channels in nerve cell membranes, preventing the generation and conduction of nerve impulses. This produces reversible loss of sensation in the area of application.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Blocks voltage-gated sodium channels in nerve cell membranes, preventing the generation and conduction of nerve impulses. This produces reversible loss of sensation in the area of application.
2D-Struktur
Cite this structure
Embed this structure
SMILES
CCN(CC)CCOC(=O)c1ccc(N)cc1Cl
InChI
InChI=1S/C13H19ClN2O2/c1-3-16(4-2)7-8-18-13(17)11-6-5-10(15)9-12(11)14/h5-6,9H,3-4,7-8,15H2,1-2H3
Molecular Formula
C13H19ClN2O2
HBD / HBA
1 / 4
Rotierbare Bindungen
7
Schwere Atome
18
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Häufig gestellte Fragen
A short-acting local anesthetic of the ester class that blocks sodium channels to reversibly inhibit nerve conduction, used primarily for epidural and spinal anesthesia in obstetric procedures. Its rapid hydrolysis by plasma cholinesterases results in a short duration of action and low systemic toxicity. It is particularly valued in obstetrics due to its rapid onset and safety profile for the neonate.
Blocks voltage-gated sodium channels in nerve cell membranes, preventing the generation and conduction of nerve impulses. This produces reversible loss of sensation in the area of application.
Yes, Chloroprocaine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1179047. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 8612. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
Medizinischer Haftungsausschluss
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
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