Dexfenfluramine

CHEMBL248702 Phase 4 Zugelassen Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

231.3 g/mol

LogP

3.4

Phase

4

The dextro-isomer of fenfluramine, an appetite suppressant that increases serotonin levels in the brain and was used for short-term weight management in obesity. It was withdrawn from the market in 1997 due to serious risks of heart valve damage and primary pulmonary hypertension. It is no longer available.

Molekularmasse

231,2600 g/mol

LogP

3,40

TPSA

12,00 Å²

Lipinski-Regel der Fünf

Bestanden

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

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SMILES

CCN[C@@H](C)Cc1cccc(C(F)(F)F)c1

InChI

InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3/t9-/m0/s1

Molecular Formula

C12H16F3N

HBD / HBA

1 / 4

Rotierbare Bindungen

4

Schwere Atome

16

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

The dextro-isomer of fenfluramine, an appetite suppressant that increases serotonin levels in the brain and was used for short-term weight management in obesity. It was withdrawn from the market in 1997 due to serious risks of heart valve damage and primary pulmonary hypertension. It is no longer available.

Yes, Dexfenfluramine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL248702. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 66265. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Struktur

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Formel: C12H16F3N

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Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.