Emedastine
This antihistamine works by blocking histamine receptors in the eye to relieve itching caused by allergic conjunctivitis. It is applied as eye drops to provide targeted relief from eye allergy symptoms.
Molekularmasse
302,4000 g/mol
LogP
2,20
TPSA
33,50 Ų
Lipinski-Regel der Fünf
Bestanden
Wirkmechanismus
Competitively blocks histamine H1 receptors on effector cells, preventing histamine-mediated vasodilation, increased vascular permeability, bronchoconstriction, and pruritus. First-generation agents also cross the blood-brain barrier, causing sedation.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Competitively blocks histamine H1 receptors on effector cells, preventing histamine-mediated vasodilation, increased vascular permeability, bronchoconstriction, and pruritus. First-generation agents also cross the blood-brain barrier, causing sedation.
2D-Struktur
Cite this structure
Embed this structure
SMILES
CCOCCn1c(N2CCCN(C)CC2)nc2ccccc21
InChI
InChI=1S/C17H26N4O/c1-3-22-14-13-21-16-8-5-4-7-15(16)18-17(21)20-10-6-9-19(2)11-12-20/h4-5,7-8H,3,6,9-14H2,1-2H3
Molecular Formula
C17H26N4O
HBD / HBA
- / 4
Rotierbare Bindungen
5
Schwere Atome
22
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Häufig gestellte Fragen
This antihistamine works by blocking histamine receptors in the eye to relieve itching caused by allergic conjunctivitis. It is applied as eye drops to provide targeted relief from eye allergy symptoms.
Competitively blocks histamine H1 receptors on effector cells, preventing histamine-mediated vasodilation, increased vascular permeability, bronchoconstriction, and pruritus. First-generation agents also cross the blood-brain barrier, causing sedation.
Yes, Emedastine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL594. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3219. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
Medizinischer Haftungsausschluss
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
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