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Esmolol

CHEMBL768 Phase 4 Zugelassen Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
295.4 g/mol
LogP
1.9
Phase
4

This fast-acting beta-blocker slows the heart rate and reduces the force of heart contractions by blocking adrenaline receptors. It is given intravenously to quickly control rapid heart rate during surgery or other urgent situations.

Molekularmasse

295,3700 g/mol

LogP

1,90

TPSA

67,80 Ų

Lipinski-Regel der Fünf

Bestanden

Therapeutische Bereiche

Cardiovascular Disease Pain Management Stroke Obesity Hypertension Breast Cancer Chronic Pain Heart Failure Atrial Fibrillation

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
COC(=O)CCc1ccc(OCC(O)CNC(C)C)cc1

                

                

                
                

                    
InChI

                    
InChI=1S/C16H25NO4/c1-12(2)17-10-14(18)11-21-15-7-4-13(5-8-15)6-9-16(19)20-3/h4-5,7-8,12,14,17-18H,6,9-11H2,1-3H3

                

                

                

                    
                    

                        
Molecular Formula

                        
C16H25NO4

                    

                    
                    

                        
HBD / HBA

                        
2 / 5

                    

                    
                    

                        
Rotierbare Bindungen

                        
10

                    

                    
                    
                    

                        
Schwere Atome

                        
21

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Häufig gestellte Fragen

                

                    
                    

                        
                        

                            
This fast-acting beta-blocker slows the heart rate and reduces the force of heart contractions by blocking adrenaline receptors. It is given intravenously to quickly control rapid heart rate during surgery or other urgent situations.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Esmolol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL768.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 59768.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Medizinischer Haftungsausschluss

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.