Febuxostat

CHEMBL1164729 Phase 4 Zugelassen Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

316.4 g/mol

LogP

3.9

Phase

4

This medication blocks the enzyme xanthine oxidase, which produces uric acid, reducing blood uric acid levels and preventing gout attacks. It is used when patients cannot tolerate allopurinol or when allopurinol is insufficient.

Molekularmasse

316,4000 g/mol

LogP

3,90

TPSA

111,00 Å²

Lipinski-Regel der Fünf

Bestanden

Therapeutische Bereiche

Cardiovascular Disease Parkinson's Disease Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Obesity Type 2 Diabetes Hypertension Gout

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

Cite this structure

Embed this structure

SMILES

Cc1nc(-c2ccc(OCC(C)C)c(C#N)c2)sc1C(=O)O

InChI

InChI=1S/C16H16N2O3S/c1-9(2)8-21-13-5-4-11(6-12(13)7-17)15-18-10(3)14(22-15)16(19)20/h4-6,9H,8H2,1-3H3,(H,19,20)

Molecular Formula

C16H16N2O3S

HBD / HBA

1 / 6

Rotierbare Bindungen

5

Schwere Atome

22

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

This medication blocks the enzyme xanthine oxidase, which produces uric acid, reducing blood uric acid levels and preventing gout attacks. It is used when patients cannot tolerate allopurinol or when allopurinol is insufficient.

Yes, Febuxostat is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1164729. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 134018. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Struktur

Schnelldaten

Formel: C16H16N2O3S
Synonyme: 1

Externe Links

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Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.