Fedratinib

CHEMBL1287853 Phase 4 Zugelassen Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

524.7 g/mol

LogP

4.8

Phase

4

This oral medication blocks JAK2, an enzyme that is overactivated in certain blood cancers, slowing the abnormal growth of blood cells. It is used to treat myelofibrosis and polycythemia vera.

Molekularmasse

524,7000 g/mol

LogP

4,80

TPSA

117,00 Å²

Lipinski-Regel der Fünf

Bestanden

Therapeutische Bereiche

Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

Cite this structure

Embed this structure

SMILES

Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1

InChI

InChI=1S/C27H36N6O3S/c1-20-19-28-26(30-21-10-12-23(13-11-21)36-17-16-33-14-5-6-15-33)31-25(20)29-22-8-7-9-24(18-22)37(34,35)32-27(2,3)4/h7-13,18-19,32H,5-6,14-17H2,1-4H3,(H2,28,29,30,31)

Molecular Formula

C27H36N6O3S

HBD / HBA

3 / 9

Rotierbare Bindungen

11

Schwere Atome

37

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

This oral medication blocks JAK2, an enzyme that is overactivated in certain blood cancers, slowing the abnormal growth of blood cells. It is used to treat myelofibrosis and polycythemia vera.

Yes, Fedratinib is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1287853. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 16722836. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

PillFYI

Suchen Sie patientenfreundliche Informationen?

Fedratinib auf PillFYI

Struktur

Schnelldaten

Formel: C27H36N6O3S
Synonyme: 1

Externe Links

Cite

BibTeX, APA, MLA, Chicago, IEEE, Harvard

Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.