Gadoxetic Acid

CHEMBL2221312 Phase 4 Zugelassen Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
681.7 g/mol
LogP
Phase
4

A gadolinium-based contrast agent used in magnetic resonance imaging of the liver, taken up selectively by functional liver cells to provide detailed images of liver structure and detect lesions such as tumors or cirrhosis. It combines the benefits of standard extracellular MRI contrast with liver-specific enhancement during the hepatobiliary phase. It helps physicians distinguish between benign and malignant liver conditions.

Molekularmasse

681,7000 g/mol

TPSA

220,00 Ų

Therapeutische Bereiche

Wirkmechanismus

Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mechanismus

Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.

2D-Struktur

SVG PNG

Cite this structure


                        

Embed this structure


                        

SMILES

[H+].[H+].CCOC1=CC=C(C=C1)C[C@@H](CN(CCN(CC(=O)[O-])CC(=O)[O-])CC(=O)[O-])N(CC(=O)[O-])CC(=O)[O-].[Gd+3]

InChI

InChI=1S/C23H33N3O11.Gd/c1-2-37-18-5-3-16(4-6-18)9-17(26(14-22(33)34)15-23(35)36)10-24(11-19(27)28)7-8-25(12-20(29)30)13-21(31)32;/h3-6,17H,2,7-15H2,1H3,(H,27,28)(H,29,30)(H,31,32)(H,33,34)(H,35,36);/q;+3/p-3/t17-;/m0./s1

Molecular Formula

C23H30GdN3O11

HBD / HBA

2 / 14

Rotierbare Bindungen

15

Schwere Atome

38

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

A gadolinium-based contrast agent used in magnetic resonance imaging of the liver, taken up selectively by functional liver cells to provide detailed images of liver structure and detect lesions such as tumors or cirrhosis. It combines the benefits of standard extracellular MRI contrast with liver-specific enhancement during the hepatobiliary phase. It helps physicians distinguish between benign and malignant liver conditions.

Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.

Yes, Gadoxetic Acid is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2221312. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 25203894. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.