Guanfacine Hydrochloride

CHEMBL1200494 Phase 4 Zugelassen Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

282.5 g/mol

LogP

—

Phase

4

A hydrochloride salt form of guanfacine, an alpha-2 agonist used in the treatment of ADHD and also studied for its cognitive-enhancing and antihypertensive properties. The extended-release hydrochloride formulation allows once-daily dosing for ADHD management. It is a non-stimulant option suitable for patients who cannot tolerate or respond inadequately to stimulant medications.

Molekularmasse

282,5000 g/mol

TPSA

81,50 Å²

Therapeutische Bereiche

Pain Management Asthma Schizophrenia Generalized Anxiety Disorder Insomnia Stroke Obesity Hypertension Major Depressive Disorder Chronic Pain Heart Failure

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

Cite this structure

Embed this structure

SMILES

Cl.N=C(N)NC(=O)Cc1c(Cl)cccc1Cl

InChI

InChI=1S/C9H9Cl2N3O.ClH/c10-6-2-1-3-7(11)5(6)4-8(15)14-9(12)13;/h1-3H,4H2,(H4,12,13,14,15);1H

Molecular Formula

C9H10Cl3N3O

HBD / HBA

3 / 1

Rotierbare Bindungen

2

Schwere Atome

16

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

A hydrochloride salt form of guanfacine, an alpha-2 agonist used in the treatment of ADHD and also studied for its cognitive-enhancing and antihypertensive properties. The extended-release hydrochloride formulation allows once-daily dosing for ADHD management. It is a non-stimulant option suitable for patients who cannot tolerate or respond inadequately to stimulant medications.

Yes, Guanfacine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200494. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 71401. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Struktur

Schnelldaten

Formel: C9H10Cl3N3O
Synonyme: 2

Externe Links

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Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.