Hydrocortisone Acetate
An ester form of hydrocortisone with slower release characteristics, used topically for inflammatory skin conditions such as eczema and dermatitis, and as intra-articular injections for joint inflammation in conditions like bursitis or arthritis. The acetate ester reduces systemic absorption from topical and joint applications, concentrating the anti-inflammatory effect locally. It is available in creams, suppositories, and injectable formulations.
Molekularmasse
404,5000 g/mol
LogP
2,20
TPSA
101,00 Ų
Lipinski-Regel der Fünf
Bestanden
Therapeutische Bereiche
Wirkmechanismus
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
2D-Struktur
Cite this structure
Embed this structure
SMILES
CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C
InChI
InChI=1S/C23H32O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-18,20,26,28H,4-9,11-12H2,1-3H3/t16-,17-,18-,20+,21-,22-,23-/m0/s1
Molecular Formula
C23H32O6
HBD / HBA
2 / 6
Rotierbare Bindungen
4
Schwere Atome
29
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Häufig gestellte Fragen
An ester form of hydrocortisone with slower release characteristics, used topically for inflammatory skin conditions such as eczema and dermatitis, and as intra-articular injections for joint inflammation in conditions like bursitis or arthritis. The acetate ester reduces systemic absorption from topical and joint applications, concentrating the anti-inflammatory effect locally. It is available in creams, suppositories, and injectable formulations.
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Yes, Hydrocortisone Acetate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1091. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5744. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
Medizinischer Haftungsausschluss
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
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