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Ibutilide Fumarate

CHEMBL2355456 Phase 4 Zugelassen Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
885.2 g/mol
LogP
—
Phase
4

This fumarate salt of ibutilide is the intravenous formulation used in hospitals to convert acute-onset atrial fibrillation or flutter to normal heart rhythm. It acts by prolonging the cardiac repolarization phase, which helps restore synchronized electrical activity. Continuous ECG monitoring is required during and after infusion due to proarrhythmic risk.

Molekularmasse

885,2000 g/mol

TPSA

231,00 Ų

Therapeutische Bereiche

Atrial Fibrillation

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CCCCCCCN(CC)CCCC(O)c1ccc(NS(C)(=O)=O)cc1.CCCCCCCN(CC)CCCC(O)c1ccc(NS(C)(=O)=O)cc1.O=C(O)/C=C/C(=O)O

                

                

                
                

                    
InChI

                    
InChI=1S/2C20H36N2O3S.C4H4O4/c2*1-4-6-7-8-9-16-22(5-2)17-10-11-20(23)18-12-14-19(15-13-18)21-26(3,24)25;5-3(6)1-2-4(7)8/h2*12-15,20-21,23H,4-11,16-17H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;;2-1+

                

                

                

                    
                    

                        
Molecular Formula

                        
C44H76N4O10S2

                    

                    
                    

                        
HBD / HBA

                        
6 / 14

                    

                    
                    

                        
Rotierbare Bindungen

                        
30

                    

                    
                    
                    

                        
Schwere Atome

                        
60

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Häufig gestellte Fragen

                

                    
                    

                        
                        

                            
This fumarate salt of ibutilide is the intravenous formulation used in hospitals to convert acute-onset atrial fibrillation or flutter to normal heart rhythm. It acts by prolonging the cardiac repolarization phase, which helps restore synchronized electrical activity. Continuous ECG monitoring is required during and after infusion due to proarrhythmic risk.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Ibutilide Fumarate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL2355456.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5281065.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Medizinischer Haftungsausschluss

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.