Indoprofen
This NSAID was developed to treat pain and inflammation but was withdrawn from the market after reports of serious gastrointestinal bleeding and other adverse effects. It worked through the standard NSAID mechanism of inhibiting prostaglandin-producing enzymes.
Molekularmasse
281,3000 g/mol
LogP
2,80
TPSA
57,60 Ų
Lipinski-Regel der Fünf
Bestanden
Wirkmechanismus
Inhibits cyclooxygenase (COX-1 and/or COX-2) enzymes, reducing the synthesis of prostaglandins and thromboxanes from arachidonic acid. This produces anti-inflammatory, analgesic, and antipyretic effects.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Inhibits cyclooxygenase (COX-1 and/or COX-2) enzymes, reducing the synthesis of prostaglandins and thromboxanes from arachidonic acid. This produces anti-inflammatory, analgesic, and antipyretic effects.
2D-Struktur
Cite this structure
Embed this structure
SMILES
CC(C(=O)O)c1ccc(N2Cc3ccccc3C2=O)cc1
InChI
InChI=1S/C17H15NO3/c1-11(17(20)21)12-6-8-14(9-7-12)18-10-13-4-2-3-5-15(13)16(18)19/h2-9,11H,10H2,1H3,(H,20,21)
Molecular Formula
C17H15NO3
HBD / HBA
1 / 3
Rotierbare Bindungen
3
Schwere Atome
21
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Häufig gestellte Fragen
This NSAID was developed to treat pain and inflammation but was withdrawn from the market after reports of serious gastrointestinal bleeding and other adverse effects. It worked through the standard NSAID mechanism of inhibiting prostaglandin-producing enzymes.
Inhibits cyclooxygenase (COX-1 and/or COX-2) enzymes, reducing the synthesis of prostaglandins and thromboxanes from arachidonic acid. This produces anti-inflammatory, analgesic, and antipyretic effects.
Yes, Indoprofen is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL15870. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3718. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
Medizinischer Haftungsausschluss
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
Embed This Widget
Add the script tag and a data attribute to embed this widget.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<div data-drugfyi="drug" data-slug="indoprofen"></div>Embed via iframe for maximum compatibility.
<iframe src="https://drugfyi.com/iframe/drug/indoprofen/" width="420" height="400" frameborder="0" style="border:0;border-radius:10px;max-width:100%" loading="lazy"></iframe>Paste this URL in WordPress, Medium, or any oEmbed-compatible platform.
https://drugfyi.com/drug/indoprofen/Add a dynamic SVG badge to your README or docs.
[](https://drugfyi.com/drug/indoprofen/)Use the native HTML custom element.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<drugfyi-drug slug="indoprofen"></drugfyi-drug>