Iotrolan
This nonionic water-soluble iodinated contrast agent was developed specifically for imaging the fluid spaces around the brain and spinal cord (myelography and cisternography). Its water solubility allows it to mix with cerebrospinal fluid and be safely absorbed, unlike older oily contrast agents.
Molekularmasse
1626,2000 g/mol
LogP
-4,20
TPSA
400,00 Ų
Lipinski-Regel der Fünf
Nicht bestanden
Wirkmechanismus
Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.
2D-Struktur
Cite this structure
Embed this structure
SMILES
CN(C(=O)CC(=O)N(C)c1c(I)c(C(=O)NC(CO)C(O)CO)c(I)c(C(=O)NC(CO)C(O)CO)c1I)c1c(I)c(C(=O)NC(CO)C(O)CO)c(I)c(C(=O)NC(CO)C(O)CO)c1I
InChI
InChI=1S/C37H48I6N6O18/c1-48(32-28(40)22(34(64)44-12(4-50)16(58)8-54)26(38)23(29(32)41)35(65)45-13(5-51)17(59)9-55)20(62)3-21(63)49(2)33-30(42)24(36(66)46-14(6-52)18(60)10-56)27(39)25(31(33)43)37(67)47-15(7-53)19(61)11-57/h12-19,50-61H,3-11H2,1-2H3,(H,44,64)(H,45,65)(H,46,66)(H,47,67)
Molecular Formula
C37H48I6N6O18
HBD / HBA
16 / 18
Rotierbare Bindungen
24
Schwere Atome
67
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Häufig gestellte Fragen
This nonionic water-soluble iodinated contrast agent was developed specifically for imaging the fluid spaces around the brain and spinal cord (myelography and cisternography). Its water solubility allows it to mix with cerebrospinal fluid and be safely absorbed, unlike older oily contrast agents.
Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.
Yes, Iotrolan is an approved drug. It has reached clinical phase 4. It is classified as a Unknown.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200555. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3738. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
Medizinischer Haftungsausschluss
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
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