Lamivudine
An antiretroviral nucleoside reverse transcriptase inhibitor used to treat HIV infection and chronic hepatitis B. It works by blocking the reverse transcriptase enzyme that HIV needs to replicate.
Molekularmasse
229,2600 g/mol
LogP
-0,90
TPSA
113,00 Ų
Lipinski-Regel der Fünf
Bestanden
Therapeutische Bereiche
Wirkmechanismus
Inhibits viral reverse transcriptase, blocking the conversion of viral RNA to DNA and preventing viral replication in infected host cells.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Inhibits viral reverse transcriptase, blocking the conversion of viral RNA to DNA and preventing viral replication in infected host cells.
2D-Struktur
Cite this structure
Embed this structure
SMILES
Nc1ccn([C@@H]2CS[C@H](CO)O2)c(=O)n1
InChI
InChI=1S/C8H11N3O3S/c9-5-1-2-11(8(13)10-5)6-4-15-7(3-12)14-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7+/m0/s1
Molecular Formula
C8H11N3O3S
HBD / HBA
2 / 4
Rotierbare Bindungen
2
Schwere Atome
15
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Häufig gestellte Fragen
An antiretroviral nucleoside reverse transcriptase inhibitor used to treat HIV infection and chronic hepatitis B. It works by blocking the reverse transcriptase enzyme that HIV needs to replicate.
Inhibits viral reverse transcriptase, blocking the conversion of viral RNA to DNA and preventing viral replication in infected host cells.
Yes, Lamivudine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL141. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 60825. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
Medizinischer Haftungsausschluss
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
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