Levomethadyl Acetate Hydrochloride
The hydrochloride salt form of levomethadyl acetate (LAAM), a long-acting opioid that was used for opioid addiction maintenance therapy. It shares the prolonged activity and cardiac risk profile of the parent compound.
Molekularmasse
390,0000 g/mol
TPSA
29,50 Ų
Wirkmechanismus
Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission …
2D-Struktur
Cite this structure
Embed this structure
SMILES
CC[C@H](OC(C)=O)C(C[C@H](C)N(C)C)(c1ccccc1)c1ccccc1.Cl
InChI
InChI=1S/C23H31NO2.ClH/c1-6-22(26-19(3)25)23(17-18(2)24(4)5,20-13-9-7-10-14-20)21-15-11-8-12-16-21;/h7-16,18,22H,6,17H2,1-5H3;1H/t18-,22-;/m0./s1
Molecular Formula
C23H32ClNO2
HBD / HBA
1 / 3
Rotierbare Bindungen
9
Schwere Atome
27
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Häufig gestellte Fragen
The hydrochloride salt form of levomethadyl acetate (LAAM), a long-acting opioid that was used for opioid addiction maintenance therapy. It shares the prolonged activity and cardiac risk profile of the parent compound.
Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.
Yes, Levomethadyl Acetate Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200817. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 39371. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
Medizinischer Haftungsausschluss
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
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