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Linezolid

CHEMBL126 Phase 4 Zugelassen Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
337.4 g/mol
LogP
0.7
Phase
4

An oxazolidinone antibiotic used to treat serious gram-positive bacterial infections, including MRSA and vancomycin-resistant enterococci. It works by blocking the early stage of bacterial protein synthesis at the ribosomal level.

Molekularmasse

337,3500 g/mol

LogP

0,70

TPSA

71,10 Ų

Lipinski-Regel der Fünf

Bestanden

Therapeutische Bereiche

Infectious Disease Bladder Cancer Chronic Kidney Disease Type 2 Diabetes Tuberculosis

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CC(=O)NC[C@H]1CN(c2ccc(N3CCOCC3)c(F)c2)C(=O)O1

                

                

                
                

                    
InChI

                    
InChI=1S/C16H20FN3O4/c1-11(21)18-9-13-10-20(16(22)24-13)12-2-3-15(14(17)8-12)19-4-6-23-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C16H20FN3O4

                    

                    
                    

                        
HBD / HBA

                        
1 / 6

                    

                    
                    

                        
Rotierbare Bindungen

                        
4

                    

                    
                    
                    

                        
Schwere Atome

                        
24

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Häufig gestellte Fragen

                

                    
                    

                        
                        

                            
An oxazolidinone antibiotic used to treat serious gram-positive bacterial infections, including MRSA and vancomycin-resistant enterococci. It works by blocking the early stage of bacterial protein synthesis at the ribosomal level.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Linezolid is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL126.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 441401.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Medizinischer Haftungsausschluss

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.