Mephentermine

CHEMBL1201234 Phase 4 Zugelassen Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

163.3 g/mol

LogP

2.4

Phase

4

This sympathomimetic amine is used in anesthesia to treat low blood pressure (hypotension) by stimulating the release of norepinephrine and directly activating adrenergic receptors to constrict blood vessels and increase cardiac output. It is particularly useful for managing the blood pressure drops that can occur during spinal or general anesthesia.

Molekularmasse

163,2600 g/mol

LogP

2,40

TPSA

12,00 Å²

Lipinski-Regel der Fünf

Bestanden

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

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SMILES

CNC(C)(C)Cc1ccccc1

InChI

InChI=1S/C11H17N/c1-11(2,12-3)9-10-7-5-4-6-8-10/h4-8,12H,9H2,1-3H3

Molecular Formula

C11H17N

HBD / HBA

1 / 1

Rotierbare Bindungen

3

Schwere Atome

12

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

This sympathomimetic amine is used in anesthesia to treat low blood pressure (hypotension) by stimulating the release of norepinephrine and directly activating adrenergic receptors to constrict blood vessels and increase cardiac output. It is particularly useful for managing the blood pressure drops that can occur during spinal or general anesthesia.

Yes, Mephentermine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201234. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 3677. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Struktur

Schnelldaten

Formel: C11H17N

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Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.