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Mesalamine

CHEMBL704 Phase 4 Zugelassen Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
153.1 g/mol
LogP
1.3
Phase
4

An anti-inflammatory drug used to treat and maintain remission of ulcerative colitis and other inflammatory bowel conditions affecting the lining of the colon. It works locally in the gut to reduce inflammation and relieve symptoms such as diarrhea, rectal bleeding, and abdominal pain.

Molekularmasse

153,1400 g/mol

LogP

1,30

TPSA

83,60 Ų

Lipinski-Regel der Fünf

Bestanden

Therapeutische Bereiche

Cardiovascular Disease Age-Related Macular Degeneration Rheumatoid Arthritis Chronic Obstructive Pulmonary Disease Melanoma Inflammatory Bowel Disease Psoriasis Multiple Sclerosis Deep Vein Thrombosis / Pulmonary Embolism Tuberculosis Colorectal Cancer

Wirkmechanismus

Increases water content in the intestinal lumen through osmotic or stimulant mechanisms, promoting bowel motility and facilitating defecation.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mechanismus

Increases water content in the intestinal lumen through osmotic or stimulant mechanisms, promoting bowel motility and facilitating defecation.

2D-Struktur

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
Nc1ccc(O)c(C(=O)O)c1

                

                

                
                

                    
InChI

                    
InChI=1S/C7H7NO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,8H2,(H,10,11)

                

                

                

                    
                    

                        
Molecular Formula

                        
C7H7NO3

                    

                    
                    

                        
HBD / HBA

                        
3 / 4

                    

                    
                    

                        
Rotierbare Bindungen

                        
1

                    

                    
                    
                    

                        
Schwere Atome

                        
11

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Häufig gestellte Fragen

                

                    
                    

                        
                        

                            
An anti-inflammatory drug used to treat and maintain remission of ulcerative colitis and other inflammatory bowel conditions affecting the lining of the colon. It works locally in the gut to reduce inflammation and relieve symptoms such as diarrhea, rectal bleeding, and abdominal pain.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Increases water content in the intestinal lumen through osmotic or stimulant mechanisms, promoting bowel motility and facilitating defecation.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Mesalamine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL704.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 4075.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Medizinischer Haftungsausschluss

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.