Methyprylon
This nonbarbiturate sedative-hypnotic was prescribed for insomnia in the 1950s-60s, working by depressing the central nervous system. It fell out of use due to risks of dependence, overdose toxicity, and the availability of safer sleep medications.
Molekularmasse
183,2500 g/mol
LogP
0,80
TPSA
46,20 Ų
Lipinski-Regel der Fünf
Bestanden
Wirkmechanismus
Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.
2D-Struktur
Cite this structure
Embed this structure
SMILES
CCC1(CC)C(=O)NCC(C)C1=O
InChI
InChI=1S/C10H17NO2/c1-4-10(5-2)8(12)7(3)6-11-9(10)13/h7H,4-6H2,1-3H3,(H,11,13)
Molecular Formula
C10H17NO2
HBD / HBA
1 / 2
Rotierbare Bindungen
2
Schwere Atome
13
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Häufig gestellte Fragen
This nonbarbiturate sedative-hypnotic was prescribed for insomnia in the 1950s-60s, working by depressing the central nervous system. It fell out of use due to risks of dependence, overdose toxicity, and the availability of safer sleep medications.
Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.
Yes, Methyprylon is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200790. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 4162. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
Medizinischer Haftungsausschluss
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
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