Naftopidil

CHEMBL142635 Phase 4 Zugelassen Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

392.5 g/mol

LogP

4.1

Phase

4

An alpha-1 adrenergic receptor blocker used in Japan and other Asian countries to treat benign prostatic hyperplasia, relieving urinary symptoms by relaxing smooth muscle in the prostate and bladder neck. It may also have benefits for sexual function.

Molekularmasse

392,5000 g/mol

LogP

4,10

TPSA

45,20 Å²

Lipinski-Regel der Fünf

Bestanden

Therapeutische Bereiche

Benign Prostatic Hyperplasia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

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SMILES

COc1ccccc1N1CCN(CC(O)COc2cccc3ccccc23)CC1

InChI

InChI=1S/C24H28N2O3/c1-28-24-11-5-4-10-22(24)26-15-13-25(14-16-26)17-20(27)18-29-23-12-6-8-19-7-2-3-9-21(19)23/h2-12,20,27H,13-18H2,1H3

Molecular Formula

C24H28N2O3

HBD / HBA

1 / 5

Rotierbare Bindungen

7

Schwere Atome

29

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

An alpha-1 adrenergic receptor blocker used in Japan and other Asian countries to treat benign prostatic hyperplasia, relieving urinary symptoms by relaxing smooth muscle in the prostate and bladder neck. It may also have benefits for sexual function.

Yes, Naftopidil is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL142635. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 4418. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Struktur

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Formel: C24H28N2O3

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Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.