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Neostigmine

CHEMBL278020 Phase 4 Zugelassen Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
223.3 g/mol
LogP
1.5
Phase
4

This medication is used to treat myasthenia gravis, a disease causing muscle weakness, and to reverse muscle relaxation after surgery. It works by preventing the breakdown of acetylcholine, a chemical messenger that allows nerve signals to reach muscles, thereby improving muscle strength.

Molekularmasse

223,2900 g/mol

LogP

1,50

TPSA

29,50 Ų

Lipinski-Regel der Fünf

Bestanden

Therapeutische Bereiche

Bladder Cancer Cardiovascular Disease Pain Management Non-Small Cell Lung Cancer Chronic Obstructive Pulmonary Disease Anesthesiology Obesity Hypertension Breast Cancer Chronic Pain

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CN(C)C(=O)Oc1cccc([N+](C)(C)C)c1

                

                

                
                

                    
InChI

                    
InChI=1S/C12H19N2O2/c1-13(2)12(15)16-11-8-6-7-10(9-11)14(3,4)5/h6-9H,1-5H3/q+1

                

                

                

                    
                    

                        
Molecular Formula

                        
C12H19N2O2+

                    

                    
                    

                        
HBD / HBA

                        
- / 2

                    

                    
                    

                        
Rotierbare Bindungen

                        
3

                    

                    
                    
                    

                        
Schwere Atome

                        
16

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Häufig gestellte Fragen

                

                    
                    

                        
                        

                            
This medication is used to treat myasthenia gravis, a disease causing muscle weakness, and to reverse muscle relaxation after surgery. It works by preventing the breakdown of acetylcholine, a chemical messenger that allows nerve signals to reach muscles, thereby improving muscle strength.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Neostigmine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL278020.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 4456.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Medizinischer Haftungsausschluss

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.