Nepafenac

CHEMBL1021 Phase 4 Zugelassen Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

254.3 g/mol

LogP

1.9

Phase

4

This non-steroidal anti-inflammatory eye drop is used to treat pain and inflammation after cataract surgery and to reduce the risk of swelling in the retina. It penetrates the eye tissues and converts to its active form to block inflammatory enzymes.

Molekularmasse

254,2800 g/mol

LogP

1,90

TPSA

86,20 Å²

Lipinski-Regel der Fünf

Bestanden

Therapeutische Bereiche

Glaucoma Age-Related Macular Degeneration Pain Management Chronic Pain

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

Cite this structure

Embed this structure

SMILES

NC(=O)Cc1cccc(C(=O)c2ccccc2)c1N

InChI

InChI=1S/C15H14N2O2/c16-13(18)9-11-7-4-8-12(14(11)17)15(19)10-5-2-1-3-6-10/h1-8H,9,17H2,(H2,16,18)

Molecular Formula

C15H14N2O2

HBD / HBA

2 / 3

Rotierbare Bindungen

4

Schwere Atome

19

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

This non-steroidal anti-inflammatory eye drop is used to treat pain and inflammation after cataract surgery and to reduce the risk of swelling in the retina. It penetrates the eye tissues and converts to its active form to block inflammatory enzymes.

Yes, Nepafenac is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1021. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 151075. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

PillFYI

Suchen Sie patientenfreundliche Informationen?

Nepafenac auf PillFYI

Struktur

Schnelldaten

Formel: C15H14N2O2
Synonyme: 2

Externe Links

Cite

BibTeX, APA, MLA, Chicago, IEEE, Harvard

Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.