Pentetate Zinc Trisodium
A zinc-containing DTPA chelating agent used to treat internal contamination with plutonium, americium, and curium, particularly when given after the first 24 hours when calcium DTPA becomes less effective. It promotes renal excretion of radioactive heavy metals.
Molekularmasse
522,7000 g/mol
TPSA
210,00 Ų
Therapeutische Bereiche
Wirkmechanismus
Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.
2D-Struktur
Cite this structure
Embed this structure
SMILES
O=C([O-])CN(CCN(CC(=O)[O-])CC(=O)[O-])CCN(CC(=O)[O-])CC(=O)[O-].[Na+].[Na+].[Na+].[Zn+2]
InChI
InChI=1S/C14H23N3O10.3Na.Zn/c18-10(19)5-15(1-3-16(6-11(20)21)7-12(22)23)2-4-17(8-13(24)25)9-14(26)27;;;;/h1-9H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25)(H,26,27);;;;/q;3*+1;+2/p-5
Molecular Formula
C14H18N3Na3O10Zn
HBD / HBA
- / 13
Rotierbare Bindungen
11
Schwere Atome
31
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Häufig gestellte Fragen
A zinc-containing DTPA chelating agent used to treat internal contamination with plutonium, americium, and curium, particularly when given after the first 24 hours when calcium DTPA becomes less effective. It promotes renal excretion of radioactive heavy metals.
Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.
Yes, Pentetate Zinc Trisodium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200424. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 164209. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
Medizinischer Haftungsausschluss
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
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