Pentolinium

CHEMBL1271 Phase 4 Zugelassen Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

240.4 g/mol

LogP

2.4

Phase

4

A ganglionic blocking agent formerly used to treat severe hypertension by blocking both sympathetic and parasympathetic ganglia, causing vasodilation and a reduction in blood pressure. It is no longer in clinical use due to its unpredictable effects and the availability of safer antihypertensives.

Molekularmasse

240,4300 g/mol

LogP

2,40

TPSA

0,00 Å²

Lipinski-Regel der Fünf

Bestanden

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

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SMILES

C[N+]1(CCCCC[N+]2(C)CCCC2)CCCC1

InChI

InChI=1S/C15H32N2/c1-16(12-6-7-13-16)10-4-3-5-11-17(2)14-8-9-15-17/h3-15H2,1-2H3/q+2

Molecular Formula

C15H32N2+2

HBD / HBA

- / -

Rotierbare Bindungen

6

Schwere Atome

17

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

A ganglionic blocking agent formerly used to treat severe hypertension by blocking both sympathetic and parasympathetic ganglia, causing vasodilation and a reduction in blood pressure. It is no longer in clinical use due to its unpredictable effects and the availability of safer antihypertensives.

Yes, Pentolinium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1271. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5850. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Struktur

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Formel: C15H32N2+2

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Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.