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Phendimetrazine

CHEMBL1615439 Phase 4 Zugelassen Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
191.3 g/mol
LogP
1.9
Phase
4

Phendimetrazine is a sympathomimetic amine and Schedule III controlled substance that functions as a norepinephrine-dopamine releasing agent to suppress appetite and increase energy expenditure. It is indicated as a short-term adjunct to diet and exercise for the treatment of obesity in adults with a BMI of 30 or greater.

Molekularmasse

191,2700 g/mol

LogP

1,90

TPSA

12,50 Ų

Lipinski-Regel der Fünf

Bestanden

Therapeutische Bereiche

Obesity

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
C[C@H]1[C@H](c2ccccc2)OCCN1C

                

                

                
                

                    
InChI

                    
InChI=1S/C12H17NO/c1-10-12(14-9-8-13(10)2)11-6-4-3-5-7-11/h3-7,10,12H,8-9H2,1-2H3/t10-,12+/m0/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C12H17NO

                    

                    
                    

                        
HBD / HBA

                        
- / 2

                    

                    
                    

                        
Rotierbare Bindungen

                        
1

                    

                    
                    
                    

                        
Schwere Atome

                        
14

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Häufig gestellte Fragen

                

                    
                    

                        
                        

                            
Phendimetrazine is a sympathomimetic amine and Schedule III controlled substance that functions as a norepinephrine-dopamine releasing agent to suppress appetite and increase energy expenditure. It is indicated as a short-term adjunct to diet and exercise for the treatment of obesity in adults with a BMI of 30 or greater.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Phendimetrazine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1615439.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 30487.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Medizinischer Haftungsausschluss

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.