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Pheniramine

CHEMBL1193 Phase 4 Zugelassen Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
240.3 g/mol
LogP
2.8
Phase
4

Pheniramine is a first-generation antihistamine of the propylamine class that competitively antagonizes H1 histamine receptors to reduce allergic symptoms, and also possesses anticholinergic and mild sedative properties. It is used in combination products for symptomatic relief of allergic conditions, common cold symptoms, and nausea.

Molekularmasse

240,3400 g/mol

LogP

2,80

TPSA

16,10 Ų

Lipinski-Regel der Fünf

Bestanden

Therapeutische Bereiche

Respiratory Disease Pain Management Rheumatoid Arthritis Gastroesophageal Reflux Disease Chronic Pain Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CN(C)CCC(c1ccccc1)c1ccccn1

                

                

                
                

                    
InChI

                    
InChI=1S/C16H20N2/c1-18(2)13-11-15(14-8-4-3-5-9-14)16-10-6-7-12-17-16/h3-10,12,15H,11,13H2,1-2H3

                

                

                

                    
                    

                        
Molecular Formula

                        
C16H20N2

                    

                    
                    

                        
HBD / HBA

                        
- / 2

                    

                    
                    

                        
Rotierbare Bindungen

                        
5

                    

                    
                    
                    

                        
Schwere Atome

                        
18

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Häufig gestellte Fragen

                

                    
                    

                        
                        

                            
Pheniramine is a first-generation antihistamine of the propylamine class that competitively antagonizes H1 histamine receptors to reduce allergic symptoms, and also possesses anticholinergic and mild sedative properties. It is used in combination products for symptomatic relief of allergic conditions, common cold symptoms, and nausea.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Pheniramine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1193.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 4761.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Medizinischer Haftungsausschluss

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.