Phenoxybenzamine

CHEMBL753 Phase 4 Zugelassen Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

303.8 g/mol

LogP

4.4

Phase

4

Used to treat episodes of high blood pressure caused by a rare adrenal gland tumor called pheochromocytoma by blocking certain receptors that normally cause blood vessels to constrict. It helps widen blood vessels and reduce blood pressure in this specific condition.

Molekularmasse

303,8000 g/mol

LogP

4,40

TPSA

12,50 Å²

Lipinski-Regel der Fünf

Bestanden

Therapeutische Bereiche

Hypertension Breast Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

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SMILES

CC(COc1ccccc1)N(CCCl)Cc1ccccc1

InChI

InChI=1S/C18H22ClNO/c1-16(15-21-18-10-6-3-7-11-18)20(13-12-19)14-17-8-4-2-5-9-17/h2-11,16H,12-15H2,1H3

Molecular Formula

C18H22ClNO

HBD / HBA

- / 2

Rotierbare Bindungen

8

Schwere Atome

21

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

Used to treat episodes of high blood pressure caused by a rare adrenal gland tumor called pheochromocytoma by blocking certain receptors that normally cause blood vessels to constrict. It helps widen blood vessels and reduce blood pressure in this specific condition.

Yes, Phenoxybenzamine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL753. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 4768. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Struktur

Schnelldaten

Formel: C18H22ClNO

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Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.