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Pirbuterol

CHEMBL1094966 Phase 4 Zugelassen Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
240.3 g/mol
LogP
-0.1
Phase
4

Pirbuterol is a selective short-acting beta-2 adrenergic receptor agonist that causes bronchodilation by relaxing bronchial smooth muscle through activation of adenylyl cyclase and increased intracellular cAMP. It is used as a bronchodilator for the relief of acute bronchospasm in asthma and other obstructive airway diseases.

Molekularmasse

240,3000 g/mol

LogP

-0,10

TPSA

85,60 Ų

Lipinski-Regel der Fünf

Bestanden

Therapeutische Bereiche

Asthma

Wirkmechanismus

Binds to and activates its target receptor, mimicking the action of the endogenous ligand to produce a specific physiological response.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mechanismus

Binds to and activates its target receptor, mimicking the action of the endogenous ligand to produce a specific physiological response.

2D-Struktur

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CC(C)(C)NCC(O)c1ccc(O)c(CO)n1

                

                

                
                

                    
InChI

                    
InChI=1S/C12H20N2O3/c1-12(2,3)13-6-11(17)8-4-5-10(16)9(7-15)14-8/h4-5,11,13,15-17H,6-7H2,1-3H3

                

                

                

                    
                    

                        
Molecular Formula

                        
C12H20N2O3

                    

                    
                    

                        
HBD / HBA

                        
4 / 5

                    

                    
                    

                        
Rotierbare Bindungen

                        
5

                    

                    
                    
                    

                        
Schwere Atome

                        
17

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Häufig gestellte Fragen

                

                    
                    

                        
                        

                            
Pirbuterol is a selective short-acting beta-2 adrenergic receptor agonist that causes bronchodilation by relaxing bronchial smooth muscle through activation of adenylyl cyclase and increased intracellular cAMP. It is used as a bronchodilator for the relief of acute bronchospasm in asthma and other obstructive airway diseases.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Binds to and activates its target receptor, mimicking the action of the endogenous ligand to produce a specific physiological response.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Pirbuterol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1094966.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 4845.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Medizinischer Haftungsausschluss

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.