Pitolisant

CHEMBL462605 Phase 4 Zugelassen Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
295.8 g/mol
LogP
4.3
Phase
4

Used to improve wakefulness in adults with narcolepsy, a condition that causes excessive daytime sleepiness and sudden episodes of muscle weakness. It works differently from other wakefulness medications by boosting the brain's natural histamine activity to promote alertness.

Molekularmasse

295,8000 g/mol

LogP

4,30

TPSA

12,50 Ų

Lipinski-Regel der Fünf

Bestanden

Therapeutische Bereiche

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

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SMILES

Clc1ccc(CCCOCCCN2CCCCC2)cc1

InChI

InChI=1S/C17H26ClNO/c18-17-9-7-16(8-10-17)6-4-14-20-15-5-13-19-11-2-1-3-12-19/h7-10H,1-6,11-15H2

Molecular Formula

C17H26ClNO

HBD / HBA

- / 2

Rotierbare Bindungen

8

Schwere Atome

20

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

Used to improve wakefulness in adults with narcolepsy, a condition that causes excessive daytime sleepiness and sudden episodes of muscle weakness. It works differently from other wakefulness medications by boosting the brain's natural histamine activity to promote alertness.

Yes, Pitolisant is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL462605. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 9948102. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.