Prenylamine

CHEMBL24072 Phase 4 Zugelassen Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

329.5 g/mol

LogP

6.0

Phase

4

Prenylamine is a calcium channel antagonist and monoamine depleting agent that was used for the treatment of angina pectoris by reducing myocardial oxygen demand through vasodilation and negative inotropic effects. It was withdrawn from many markets due to its propensity to cause QT prolongation and potentially fatal ventricular arrhythmias, particularly torsades de pointes.

Molekularmasse

329,5000 g/mol

LogP

6,00

TPSA

12,00 Å²

Lipinski-Regel der Fünf

Bestanden

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

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SMILES

CC(Cc1ccccc1)NCCC(c1ccccc1)c1ccccc1

InChI

InChI=1S/C24H27N/c1-20(19-21-11-5-2-6-12-21)25-18-17-24(22-13-7-3-8-14-22)23-15-9-4-10-16-23/h2-16,20,24-25H,17-19H2,1H3

Molecular Formula

C24H27N

HBD / HBA

1 / 1

Rotierbare Bindungen

8

Schwere Atome

25

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

Prenylamine is a calcium channel antagonist and monoamine depleting agent that was used for the treatment of angina pectoris by reducing myocardial oxygen demand through vasodilation and negative inotropic effects. It was withdrawn from many markets due to its propensity to cause QT prolongation and potentially fatal ventricular arrhythmias, particularly torsades de pointes.

Yes, Prenylamine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL24072. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 9801. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Struktur

Schnelldaten

Formel: C24H27N

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Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.