Procyclidine

CHEMBL86715 Phase 4 Zugelassen Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
287.4 g/mol
LogP
4.1
Phase
4

Procyclidine is an anticholinergic antiparkinsonian agent that blocks muscarinic acetylcholine receptors in the striatum, thereby reducing the relative excess of cholinergic tone resulting from dopaminergic deficiency in Parkinson's disease and drug-induced parkinsonism. It is used for the management of tremor and rigidity in Parkinson's disease and for extrapyramidal side effects caused by antipsychotic medications.

Molekularmasse

287,4000 g/mol

LogP

4,10

TPSA

23,50 Ų

Lipinski-Regel der Fünf

Bestanden

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

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SMILES

OC(CCN1CCCC1)(c1ccccc1)C1CCCCC1

InChI

InChI=1S/C19H29NO/c21-19(17-9-3-1-4-10-17,18-11-5-2-6-12-18)13-16-20-14-7-8-15-20/h1,3-4,9-10,18,21H,2,5-8,11-16H2

Molecular Formula

C19H29NO

HBD / HBA

1 / 2

Rotierbare Bindungen

5

Schwere Atome

21

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

Procyclidine is an anticholinergic antiparkinsonian agent that blocks muscarinic acetylcholine receptors in the striatum, thereby reducing the relative excess of cholinergic tone resulting from dopaminergic deficiency in Parkinson's disease and drug-induced parkinsonism. It is used for the management of tremor and rigidity in Parkinson's disease and for extrapyramidal side effects caused by antipsychotic medications.

Yes, Procyclidine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL86715. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 4919. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.