Promethazine
A versatile medication used to treat allergies, motion sickness, nausea, and vomiting, and also used as a sedative before and after surgery. It works by blocking histamine receptors to reduce allergy symptoms and dopamine receptors to control nausea.
Molekularmasse
284,4000 g/mol
LogP
4,80
TPSA
31,80 Ų
Lipinski-Regel der Fünf
Bestanden
Therapeutische Bereiche
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D-Struktur
Cite this structure
Embed this structure
SMILES
CC(CN1c2ccccc2Sc2ccccc21)N(C)C
InChI
InChI=1S/C17H20N2S/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19/h4-11,13H,12H2,1-3H3
Molecular Formula
C17H20N2S
HBD / HBA
- / 3
Rotierbare Bindungen
3
Schwere Atome
20
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Häufig gestellte Fragen
A versatile medication used to treat allergies, motion sickness, nausea, and vomiting, and also used as a sedative before and after surgery. It works by blocking histamine receptors to reduce allergy symptoms and dopamine receptors to control nausea.
Yes, Promethazine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL643. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 4927. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
Medizinischer Haftungsausschluss
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
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